病理学教研室 - 汕头大学医学院 Shantou University Medical College

病理学教研室

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研究成果

1. Lin RH#, Xiao DJ#, Guo Y, Tian DP,, Yun HL, Chen D, Su M*, Chronic inflammation-related DNA damage response: a driving force of gastric cardia carcinogenesis. Oncotarget. 2015 Feb 20;6(5):2856-64.

2. Zhang JF, Zhou GZ, Tian DP, Lin RH, Peng GY, Su M*, Microdissection of Human Esophagogastric Junction Wall with Phase-contrast X-ray CT Imaging. Sci Rep. 2015 Sep 8;5:13831.

3. Zhang GH, Cheng YB, Chen GD, Tang Y, Ardekani G, Rotte A, Martinka M, McElwee KJ, Xu X, Wang Q and Zhou YW. Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis. Oncotarget. 2015; 6(26):23026-35

4. Mai RQ, Zhou SX, Zhong WX, Rong SM, Cong ZC, Li YX, Xie QZ, Chen HM, Li XY, Liu SH, Cheng YB, Huang YS, Zhou YW, Zhang GH*. Therapeutic efficacy of combined BRAF and MEK inhibition in metastatic melanoma: a comprehensive network meta-analysis of randomized controlled trials. Oncotarget. 2015; 6(29):28502-12

5. Cheng YB, Tang Y, Chen GD, Safaee Ardekani G, Jafarnejad SM, Rotte A, McElwee KJ, Zhang GH* and Zhou YW*. Stage-Specific Prognostic Biomarkers for Melanoma. Oncotarget. 2015; 6(6):4180-9

6. Runhua Lin#, Chong Zhang#, Jiaxuan Zheng#, Dongping Tian, Zhijin Lei, Donglin Chen, Zexin Xu, Min Su*,Chronic inflammation-associated genomic instability paves the way for human esophageal carcinogenesis, Oncotarget. 2016 Mar 25

7. Zhijin Lei, Dongping Tian, Chong Zhang, Shukun Zhao, Min Su*. Clinicopathological and prognostic significance of GPX2 protein expression in esophageal squamous cell carcinoma. BMC Cancer. 2016 Jul 7;16:410. doi: 10.1186/s12885-016-2462-3.

8. Yuanyuan Wang, Shaohong Wang, Jinhui Shen,Yanyan Peng, Lechuan Chen,Ruiqin Mai, and Guohong Zhang*,Genotype Distribution of Human Papillomavirus among Women with Cervical Cytological Abnormalities or Invasive Squamous Cell Carcinoma in a High-Incidence Area of Esophageal Carcinoma in China.Biomed Res Int.2016;2016:1256384.

9. Shaoqi Chen, YukaiWang*, Guohong Zhang*, and Shigao Chen.Combination of Salivary Gland Ultrasonography and Virtual Touch Quantification for Diagnosis of Sjogren's Syndrome: A Preliminary Study.Biomed Res Int. 2016;2016:2793898.

10. Liu X#, Zhang M#, Ying SM#, Zhang C, Lin RH, Zheng JX, Zhang GH, Tian DP, Guo Y, Du CW, Chen YP, Chen SB, Su X, Ji J, Deng WT, Li X, Qiu SY, Yan RJ, Xu ZX, Wang Y, Guo YN, Cui JC, Zhuang SS, Yu H, Zheng Q, Marom M, Sheng ST, Zhang GQ, Hu SN, Li RQ, Su M*.Genetic Alterations in Esophageal Tissues From Squamous Dysplasia to Carcinoma.Gastroenterology. 2017 Mar 30. pii: S0016-5085(17)30342-6. doi: 10.1053/j.gastro.2017.03.033.

11. Liu SH, Chen GC, Huang HH, Lin W, Guo D, Zhao S, Tian DP*, Su M*. Patrilineal background of the She minority population from Chaoshan Fenghuang Mountain, an isolated mountain region, in China.Genomics. 2017 May 7. pii: S0888-7543(17)30033-2. doi: 10.1016/j.ygeno.2017.05.002.

12. Ying Zhang*, Yelong Chen, Hailong Yun, Zhaoyong Liu, Min Su and Raymond Lai, STAT1 beta enhances STAT1 function by protecting STAT1 alpha from degradation in esophageal squamous cell carcinoma,Cell Death Dis. 2017 Oct 5;8(10):e3077

13. Songxia Zhou, Weixiang Zhong, Ruiqin Mai, and Guohong Zhang*, Mammary and Extramammary Paget's Disease Presented Different Expression Pattern of Steroid Hormone Receptors, Biomed Res Int. 2017; 2017: 3768247.

14. Ruiqin Mai, Songxia Zhou, Shuqin Zhou, Weixiang Zhong,Liangli Hong, Yuanyuan Wang, Shanming Lu, Jikai Pan,Yuansheng Huang, Mingwan Su, Richard Crawford, Youwen Zhou,Guohong Zhang,⁎Transcriptome analyses reveal FOXA1 dysregulation in mammary and extramammary Paget's disease, Hum Pathol. 2018 Jul;77:152-158.

15. Ruijing Yan,Yi Guo ,Qingyun Gong,Man Chen ,Yuanning Guo ,Peng Yang ,Hao Huang ,Haihua Huang ,Wen Huang ,Zikai Ma ,Zhijian Zheng ,Dongping Tian ,Min Su* Microbiological evidences for gastric cardiac microflora dysbiosis inducing the progression of inflammation,Journal of Gastroenterology and Hepatology, J Gastroenterol Hepatol. 2020 Jun;35(6):1032-1041.doi: 10.1111/jgh.14946. Epub 2020 Jan 29.

16. Xiang Li #, Dongping Tian#, Yi Guo#，Shiyue Qiu, Zexin Xu, Wen Deng, Min Su*，Genomic characterization of a newly established esophageal squamous cell carcinoma cell line from China and published esophageal squamous cell carcinoma cell lines, Cancer Cell Int. 2020 May 24;20:184. doi: 10.1186/s12935-020-01268-x. eCollection 2020.

17. Guo Yuan-ning#, Tian Dong-ping#, Gong Qing-yun, Huang Hao, Yang Peng, Chen Shao-bin, Billan Salem, He Jia-yu, Huang Hai-Hua, Xiong Pan, Lin Wen-ting, Guo Dan, Marom Moshe, Gil Ziv*, Su Min*. Perineural Invasion is a Better Prognostic Indicator than Lymphovascular Invasion and a Potential Adjuvant Therapy Indicator for pN0M0 Esophageal Squamous Cell Carcinoma， Annals of Surgical Oncology, 2020, 27(11): 4371-4381

18. Guo Yuan-ning, Su Min*. ASO Author Reflections: Perineural Invasion in pN0M0 Esophageal Squamous Cell Carcinoma: Let Pathology Strengthen the Clinical Oncology Practice.Ann Surg Oncol. 2020 Oct;27(11):4382-4383.

19. Runhua Lin*, Chenxi Li , Zhaohui Liu , Ruinuan Wu, Jianghong Lu, Genome-wide DNA methylation profiling identifies epigenetic signatures of gastric cardiac intestinal metaplasia.J Transl Med.2020 Jul 31;18(1):292.

20. Yukai Wang , Shaoqi Chen, Jingyao Chen, Xuezhen Xie, Sini Gao,Chengpeng Zhang,Songxia Zhou, Jing Wang, Ruiqin Mai, Qisheng Lin,Jianqun Lin, Marco Matucci-Cerinic, Guohong Zhang* ,Daniel E Furst Germline genetic patterns underlying familial rheumatoid arthritis, systemic lupus erythematosus and primary Sjren’s syndrome highlight T cell-initiated autoimmunity. Ann Rheum Dis 2020;79:268–275.

21. Jingyao Chen, Di Xia, Muming Xu, Ruibing Su, Wenting Lin, Dan Guo,Guangcan Chen* and Shuhui Liu*,Expression and Significance of MyD88 in Patients With Gastric Cardia Cancer in a High-Incidence Area of China.Front Oncol, 2020 May 14;10:559.

22. Hao Ye #, Xiang Li # , Jing Lin, Peng Yang, Min Su*. CD98hc has a pivotal role in maintaining the immuno-barrier integrity of basal layer cells in esophageal epithelium.Cancer Cell Int. 2022 Feb 22;22(1):98.

23. Ruibing Su #, Lijun Cai #, Pan Xiong #, Zhiwei Liu #, Shaobin Chen, Xi Liu, Runhua Lin, Zhijin Lei, Dongping Tian, Min Su*.TLR3 Expression is a Potential Prognosis Biomarker and Shapes the Immune-Active Tumor Microenvironment in Esophageal Squamous Cell Carcinoma.J Inflamm Res. 2022 Feb 28;15:1437-1456.

24. Anil Ahsan# , Zhiwei Liu#, Ruibing Su, Chencai Liu, Xiaoqi Liao and Min Su * Potential Chemotherapeutic Effect of Selenium for Improved Canceration of Esophageal Cancer, Int J Mol Sci. 2022 May 14;23(10):5509. doi: 10.3390/ijms23105509.

25. Jinfu Chen, Bowen Cheng, Wei Xie, Min Su* .Occupational Dust Exposure and Respiratory Protection of Migrant Interior Construction Workers in Two Chinese Cities, Int J Environ Res Public Health. 2022 Aug 16;19(16):10113.doi: 10.3390/ijerph191610113.

26. Zhiwei Liu#, Ruibing Su#, Anil Ahsan, Chencai Liu, Xiaoqi Liao, Dongping Tian, Min Su*,Esophageal Squamous Cancer from 4NQO-Induced Mice Model: CNV Alterations Int J Mol Sci. 2022 Nov 18;23(22):14304.doi: 10.3390/ijms232214304.

27. Jinfu Chen, Shaose Ye, Ling Mao, Wei Xie, Huan Nie, Min Su*Characteristics and factors associated with morbidity of migrant workers with pneumoconiosis: a cross-sectional study. BMJ Open. 2022 Nov 11;12(11):e064596.doi: 10.1136/bmjopen-2022-064596.

28. Runhua Lin, Yanli Qian, Jinhai Zhang, Di Xia, Dongming Guo, Liangli Hong, Bojuan Qing, Muming Xu, Yiteng Huang, Wenting Lin, Guangcan Chen*, Shuhui Liu*. Genome-wide DNA methylation profiling of gastric cardia cancer. J Gastroenterol Hepatol. 2022 Nov 7. doi: 10.1111/jgh.16054.

29. Zhen Lin , John T M Plukker, Dong-Ping Tian, Shao-Bin Chen, Gursah Kats-Ugurlu*, Min Su*. Identification and Prognostic Effect of Extramural Venous Invasion in Locally Advanced Esophageal Squamous Cell Carcinoma. Am J Surg Pathol, 2023, 47(7): 766-73.

30. Xiaoqi Liao #, Runhua Lin#, Zhihua Zhang, Dongping Tian, Zhaohui Liu, Songqin Chen, Guohua Xu, Min Su*,Genome-wide DNA methylation and transcriptomic patterns of precancerous gastric cardia lesions.J Natl Cancer Inst. 2024 May 8;116(5):681-693.

31. Tianzhong Ma, Songxia Zhou, Xuezhen Xie, Jingyao Chen, Jing Wang, Guohong Zhang #，A case report of a family with developmental arrest of human prokaryotic stage zygote，Front Cell Dev Biol. 2024 Mar 28:12:1280797.

32. Xi Liu , Lijun Cai, Juan Ji, Dongping Tian, Yi Guo, Shaobin Chen, Meng Zhao, Min Su#. Genomic characteristics and evolution of Multicentric Esophageal and gastric Cardiac Cancer.Biol Direct. 2024 Jul 1;19(1):51.

33. Jiamin Chen, Xi Liu, Zhihua Zhang, Ruibing Su, Yiqun Geng, Yi Guo, Yimin Zhang, Min Su# .Early Diagnostic Markers for Esophageal Squamous Cell Carcinoma: Copy Number Alteration Gene Identification and cfDNA Detection.Lab Invest. 2024 Oct;104(10):102127.