广东省感染病与分子免疫病理重点实验室
研究成果

(附本中心近三年部分研究成果)

1. Wei Liu # 1 2, Lei Xie # 1, Yao-Hui He # 3 4, Zhi-Yong Wu # 5, Lu-Xin Liu # 1, Xue-Feng Bai 6, Dan-Xia Deng 1, Xiu-E Xu 1, Lian-Di Liao 1, Wan Lin 1, Jing-Hua Heng 1, Xin Xu 1, Liu Peng 1, Qing-Feng Huang 1, Cheng-Yu Li 1, Zhi-Da Zhang 1, Wei Wang 2, Guo-Rui Zhang 6, Xiang Gao 3 4, Shao-Hong Wang 5, Chun-Quan Li 6, Li-Yan Xu 7, Wen Liu 8 9, En-Min Li 10 Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting. Nat Commun.2021 Aug 16;12(1):4961.

2. Huy Q Dinh # 1 2, Feng Pan # 3 4, Geng Wang # 4 5, Qing-Feng Huang # 3 4, Claire E Olingy 6, Zhi-Yong Wu 7, Shao-Hong Wang 7, Xin Xu 3 4, Xiu-E Xu 3 4, Jian-Zhong He 3 4, Qian Yang 8, Sandra Orsulic 9, Marcela Haro 9, Li-Yan Li 3, Guo-Wei Huang 3, Joshua J Breunig 10, H Phillip Koeffler 8, Catherine C Hedrick 6, Li-Yan Xu 11 12, De-Chen Lin 13, En-Min Li 14 15. Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment. Nat Commun. 2021 Dec 17;12(1):7335.

3. Zhen-Yuan Zheng 1, Ping-Lian Yang 2, Rong-Yao Li 1, Lu-Xin Liu 1, Xiu-E Xu 2, Lian-Di Liao 2, Xiang Li 2, Man-Yu Chu 2, Liu Peng 1, Qing-Feng Huang 2, Jing-Hua Heng 2, Shao-Hong Wang 3, Zhi-Yong Wu 3, Zhi-Jie Chang 4, En-Min Li 5, Li-Yan Xu 6  STAT3β disrupted mitochondrial electron transport chain enhances chemosensitivity by inducing pyroptosis in esophageal squamous cell carcinoma. Cancer Lett  2021 Dec 1;522:171-183.

4. Yukai Wang # 1, Xuezhen Xie # 1, Chengpeng Zhang 2, Miaotong Su 2, Sini Gao 2, Jing Wang 2, Changhao Lu 2, Qisheng Lin 1, Jianqun Lin 1, Marco Matucci-Cerinic 3, Daniel E Furst 4, Guohong Zhang 5 Rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren's syndrome shared megakaryocyte expansion in peripheral blood. Ann Rheum Dis. 2022 Mar;81(3):379-385.

5. Liming Gu 1 2, Huixiong Deng 1 2, Zhihui Ren 1 3, Ying Zhao 1 2, Shun Yu 1 2, Yingzhu Guo 1 2, Jianping Dai 1 2, Xiaoxuan Chen 1 2, Kangsheng Li 1 2, Rui Li 1 2, Gefei Wang 1 2 Dynamic Changes in the Microbiome and Mucosal Immune Microenvironment of the Lower Respiratory Tract by Influenza Virus Infection. Front Microbiol. 2019 Nov 1;10:2491.

6. Xiang Zeng 1, Judith M Vonk 2, Diana A van der Plaat 2, Alen Faiz 3, Peter D Paré 4, Philippe Joubert 5, David Nickle 6, Corry-Anke Brandsma 3, Hans Kromhout 7, Roel Vermeulen 7, Xijin Xu 8, Xia Huo 9, Kim de Jong 2, H Marike Boezen 10  Genome-wide interaction study of gene-by-occupational exposures on respiratory symptoms. Environ Int. 2019 Jan;122:263-269.

7. Shumin Huang 1 2, Xiaoxin Huang 1 2, Ran Bi 3, Qiuxia Guo 4, Xiaolin Yu 5, Qinghui Zeng 5, Ziyu Huang 1, Tianming Liu 1, Haisheng Wu 5, Yuliang Chen 5, Jialong Xu 1, Yinge Wu 1, Pi Guo 5 6  Detection and Analysis of Microplastics in Human Sputum. Environ Sci Technol  2022 Feb 15;56(4):2476-2486.

8. Xiaoqiang Yang 1 2 3 4, Weiwen Cai 1 2 3, Xiaoyue Sun 1 2 3, Yanwei Bi 1 2 3, Chui Zeng 1 2 3, XiaoYu Zhao 1 2 3, Qi Zhou 1 2 3, Tian Xu 3, Qingdong Xie 1 2 3, Pingnan Sun 1 2 3, Xiaoling Zhou 1 2 3 Defined host factors support HBV infection in non-hepatic 293T cells. J Cell Mol Med. 2020 Feb;24(4):2507-2518.

9. Qian Xu 1, Xiaodong Deng 1 2, Biying Zhang 1, Chanyuan Zhao 1, Tao Huang 1, Yimin Zhang 1 3, Zhiming Chen 1 3, Jiang Gu 4 5  A study of the possible role of Fab-glycosylated IgG in tumor immunity Cancer Immunol Immunother. 2021 Jul;70(7):1841-1851.

10. Yueyan Liao 1, Xiangyu Ke 1, Tianyi Deng 1, Qingsong Qin 1 2 3 The Second-Generation XPO1 Inhibitor Eltanexor Inhibits Human Cytomegalovirus (HCMV) Replication and Promotes Type I Interferon Response. Front Microbiol. 2021 May 3;12:675112.